Negative Thermo-responsive Microspheres Based on Hydrolyzed Gelatin as Drug Delivery Device
نویسندگان
چکیده
منابع مشابه
Thermo- and pH-responsive polymers in drug delivery.
Stimuli-responsive polymers show a sharp change in properties upon a small or modest change in environmental condition, e.g. temperature, light, salt concentration or pH. This behaviour can be utilised for the preparation of so-called 'smart' drug delivery systems, which mimic biological response behaviour to a certain extent. The possible environmental conditions to use for this purpose are li...
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In the long-term management of ulcerative colitis patients, repeat dosing maybe required. Since 5-ASA is largely absorbed from the upper intestine, selective delivery of drugs into the colon may be regarded as a better method of drug delivery with fewer side effects and a higher efficacy. The aim of this study was to prepare and evaluate a double coated multiparticulate system for 5-ASA deliver...
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1961 B. Sree Giri Prasad* Teegala Krishna Reddy College of Pharmacy, Meerpet, Medbowli, Hyderabad, A.P, Email: [email protected] [email protected] Mobile No: 09441893479 Address for correspondence Oral modified-release multiple-unit dosage forms have always been more effective therapeutic alternative to conventional or immediate release single-unit dosage forms. With regar...
متن کاملDrug delivery from gelatin-based systems.
INTRODUCTION Carriers for controlled drug release offer many advantages compared with conventional dosage forms. Gelatin has been investigated extensively as a drug delivery carrier, due to its properties and history of safe use in a wide range of medical applications. AREAS COVERED Gelatin was shown to be versatile due to its intrinsic features that enable the design of different carrier sys...
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In the long-term management of ulcerative colitis patients, repeat dosing maybe required. Since 5-ASA is largely absorbed from the upper intestine, selective delivery of drugs into the colon may be regarded as a better method of drug delivery with fewer side effects and a higher efficacy. The aim of this study was to prepare and evaluate a double coated multiparticulate system for 5-ASA deliver...
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ژورنال
عنوان ژورنال: AAPS PharmSciTech
سال: 2010
ISSN: 1530-9932
DOI: 10.1208/s12249-010-9429-5